In our research group we are investigating simple chemical models for the signaling process in the nervous system. There are three main processes in neuronal signaling: the generation of small signaling molecules, such as glutamic acid, acetylcholine, or nitric oxide. These neurotransmitters transport information over the synaptic cleft. The second part deals with detection and sensing of these molecules and other bioanalytes. The third part reveals signal processing and relaying. We are addressing all three parts with materials, bioinorganic and supramolecular analytical chemistry concepts.
Photo-inducible nitric oxide and carbon monoxide-releasing molecules and materials & remote controlled delivery
Sugar sensing at physiological conditions (fluorescence, 19F NMR) and analyte discrimination
Molecular logic and computing with sensors and light